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Support for patients prescribed NERLYNX
  • Benefits Verification and Prior Authorization Assistance

    Our Nurse Case Manager will conduct a benefits investigation, verify insurance approval or coverage, and obtain and submit necessary documentation for patients requiring prior authorization.

  • NERLYNX Quick Start

    Puma Biotechnology provides a free 3-week supply of NERLYNX to eligible patients experiencing delays in gaining access to therapy.

  • Co-Pay Assistance

    Puma Biotechnology offers co-pay assistance to help qualified insured patients with the out-of-pocket costs associated with their NERLYNX prescription.

  • Financial Support

    For patients with financial needs, we will work to find appropriate sources for support.

  • NERLYNX Mentor Program

    This program is available to all patients with HER2+ breast cancer who are considering or currently taking NERLYNX.

  • Nurse Support

    Our nurses are available to speak with patients and healthcare providers to answer questions about NERLYNX. The call center is open Monday through Friday, 9 AM - 8 PM EST.

  • Product Support

    Our specialty pharmacy network will provide patients with product education and side-effect counseling to help them better understand and manage their NERLYNX therapy.

  • Text Message Support

    Patients can sign up to receive medication reminders and motivational messages to support treatment adherence.

Supportive Care Voucher Program
  • Up to 3 months’ free supply per antidiarrheal product

  • Available to all patients

  • Used at the dispensing pharmacy, with prescription(s) at local retail pharmacy, or through Puma Specialty Pharmacy network

For more information on the Puma Patient Lynx Support Program, call 1-855-816-5421.
How to get NERLYNX
NERLYNX is available through specific specialty pharmacies. To learn about reimbursement, download the form below.
  • AcariaHealth
    T: (800) 511-5144 F: (877) 541-1503
    Hours of operation:
    M-F, 8 am–10 pm (ET)
  • Biologics, Inc.
    T: (800) 850-4306 F: (800) 823-4506
    Hours of operation:
    M-F, 8 am–8 pm (ET)
  • Optum® Specialty Pharmacy
    T: (855) 427-4682 F: (800) 491-7997
    Hours of operation:
    Every day, 7 am–10 pm (CST)
  • Accredo® Health Group, Inc.
    T: (877) 732-3431 F: (866) 352-3973
    Hours of operation:
    M-F, 8 am–11 pm (ET)
  • CVS Caremark Specialty Pharmacy
    T: (844) 239-4761 F: (855) 296-0210
    Hours of operation:
    M-F, 8:30 am–8:30 pm (ET)
  • Onco360®
    T: (877) 662-6633 F: (877) 662-6355
    Hours of operation:
    M-F, 8 am–7 pm (ET); Sat., 9 am–2 pm (ET)

National Drug Code (NDC)

NERLYNX 40 mg film-coated tablets
Package Size: 180 tablets
NDC: 70437-240-18

The NERLYNX patient co-pay card is available
Puma Biotechnology offers co-pay assistance to help qualified insured patients with the out-of-pocket costs associated with their NERLYNX prescription.
Commercially insured, eligible patients treated with NERLYNX may pay as little as $10 per prescription.* Patients will be enrolled through their specialty pharmacy. To verify your patients' eligibility or to enroll them in the co-pay card program, visit this website or call Puma Patient Lynx at 1-855-816-5421.
*Limitations apply. Patient must have commercial insurance. Offer is not valid under Medicare, Medicaid, or any other federal or state program. Puma Biotechnology reserves the right to rescind, revoke, or amend this program without notice. For full terms and conditions, call 1-855-816-5421.


NERLYNX® (neratinib) tablets, for oral use

INDICATIONS AND USAGE: NERLYNX is a kinase inhibitor indicated:



ADVERSE REACTIONS: The most common adverse reactions (reported in ≥5% of patients) were:

To report SUSPECTED ADVERSE REACTIONS, contact Puma Biotechnology, Inc. at 1-844-NERLYNX (1-844-637-5969) or FDA at 1-800-FDA-1088 or



For Full Prescribing Information, please click here.